MUCINOUS COLORECTAL CANCER 

Br J Cancer. 2013 May 7. doi: 10.1038/bjc.2013.232. [Epub ahead of print]

Prognostic implication of mucinous histology in colorectal cancer patients treated with adjuvant FOLFOX chemotherapy.

Lee DW, Han SW, Lee HJ, Rhee YY, Bae JM, Cho NY, Lee KH, Kim TY, Oh DY, Im SA, Bang YJ, Jeong SY, Park KJ, Park JG, Kang GH, Kim TY.

Source

Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.

Abstract

Background:There have been controversies in prognostic impact of mucinous histology on colorectal cancer, and its implication in patients treated with adjuvant 5-fluorouracil, leucovorin, and oxaliplatin (FOLFOX) is unclear.Methods:Stage II and III colorectal cancer patients who underwent curative resection followed by adjuvant FOLFOX were included. Patients were grouped according to the mucinous content: >50%, mucinous adenocarcinoma (MAC); <50 2013="" 27="" 3.76-16.8="" 41="" 453="" 521="" 57="" 7.96="" 7="" 86="" 87="" 95="" a="" adenocarcinoma="" adjusted="" adjuvant="" advance="" adverse="" aim="" an="" analysis="" and="" angiolymphatic="" any="" as="" bjc.2013.232="" but="" cancer="" clinicopathological="" colorectal="" compared.results:among="" compared="" component="" confidence="" dfs="" disease-free="" distinct="" doi:10.1038="" factor="" features="" folfox.british="" frequency="" had="" has="" have="" hazard="" higher="" ii="" iii="" impact="" in="" independent="" instability="" intermediated="" interval="" invasion.="" journal="" location="" lower="" mac="" may="" microsatellite="" mucinous="" multivariate="" negative="" nma.="" nma="" non-mac="" of="" on="" onclusion:adenocarcinoma="" online="" or="" p="" patients="" prognostic="" proximal="" publication="" ratio="" respectively="" revealed="" significantly="" stage="" survival="" the="" total="" treated="" vs="" was="" were="" with="" without="" worse="" www.bjcancer.com.="" year="">