Overexpressed gene may be linked to ovarian cancer.
WebMD (12/11, Warner) reported, "Researchers found a gene called MAGP2, which has not previously been associated with any type of cancer, was overexpressed in the most fatal types of ovarian cancer," according to a study published in the journal Cancer Cell. In "samples from 53 advanced papillary serous ovarian cancer tumors," researchers found that "the MAGP2 gene was overexpressed in...women who died most quickly from their cancer. Further testing showed MAGP2 levels were also higher than normal in another group of ovarian cancer tumors, but not in normal ovarian tissue." Meanwhile, "levels of MAGP2 were lower in women whose tumors responded well to chemotherapy."
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