NEW YORK (Reuters Health) Jan 07 - Men who develop primary breast cancer usually present with an irregular subareolar mass with speculated or indistinct margins on mammography, according to a report in the December issue of the American Journal of Radiology.
"These tumors usually present late with a palpable or clinical finding, such as change in overlying skin or nipple," Dr. Wei-Tse Yang from The University of Texas M. D. Anderson Cancer Center, Houston, told Reuters Health. "Be attentive to any palpable masses in men and obtain imaging evaluation early."
Dr. Yang and colleagues described the mammographic, sonographic, and histopathologic findings of primary breast cancer in 244 men, including the axillary nodal status as determined by sonography.
Only 57 of 244 men with primary breast cancer underwent preoperative mammography or sonography, the authors report, and most of these patients presented with a palpable mass (54 of 57) or nipple inversion (2 of 57) or nipple discharge.
Mammographic findings included a noncalcified mass only (69%), a mass with microcalcifications (29%), or microcalcifications only (2%), the report indicates.
The masses were most frequently irregular (50%) with speculated (33%) or indistinct (32%) margins. Masses were either directly subareolar (58%) or eccentric (42%), and 40% of men also had gynecomastia.
Sonography showed visible masses in 90% of men with cancer, the researchers note, and 30% of men had abnormal axillary nodes by sonography.
Histopathology revealed invasive ductal cancer in most cases (51%), and most tumors were positive for estrogen (93%) or progesterone (79%) receptors.
"The clinical implications of this study are that punctuate calcifications on mammography and circumscribed masses on sonography can be associated with cancer in men," the investigators say. "Radiologists should be aware of these findings to avoid the misdiagnosis of cancer in men as a benign lesion."
"We plan to extend the study to include more patients," Dr. Yang said.
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It is important that the results obtained after surgery does not necessarily correspond to what you have in mind as the ideal shape of the breast.
The presence of a breast implant makes it technically difficult to detect the growth of breast cancer with mammography. However, all these reasons, did not do women reconsider their search for better through surgery for breast cancer.
There are other more complex problems that can increase ones chances of gynecomastia. It is known that obesity increases estrogen levels so that with increased body fat, man boobs may result. What causes man boobs to continue on past puberty may be a hormone balance or high body fat or a combination of both.
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